Efficacy testing

Efficacy testing: redness reduction

Study design

General skin testing protocol

Number of subjects

20 (determined by client)

Place of application

Face / Arm / Thigh (determined by client)

Testing time

4 weeks (determined by client)

Sample requirement

Equal to the number of subjects

Measurement points

  • T0 – before application (cleaned skin surface, adaptation time 20 min)
  • Tx – after x weeks (determined by client)

Procedure

  • Washout phase at least 2 h before the measurement
  • 3–5 measurements on the testing site (“BEFORE testing”)
  • Product used by participants at home during the testing period
  • 3–5 measurements on the testing site (“AFTER testing”)

Equipment

  • Demaflex / Dermalab (Cortex Technologies)
  • Soft FX (Callegari, 1930)
  • EVE M Panoramic AI skin analyzer
Signs & claims

Signs of redness

Facial skin analysis on the EVE M skin analyzer

Redness can manifest in various ways. Some common signs are visible red hue, blushed appearance, warmth, itching, burning sensation, swelling, stinging.

Addressing redness involves identifying and addressing the cause. We recommend avoiding triggers, using gentle skincare products, protecting skin.

Claims related to skin redness

  • Redness reduction
Methodology

Measurement principles and instruments.

Skin colour measurement with Dermalab

To prove redness reduction claims we measure the following parameters using the following instruments:

  • Skin colour evaluation
    • Dermalab (Cortex Technologies)
Evidence

See our results.

Erythema values (redness) over time
Skin erythema and melanin values per subject
Skin reaction

Redness

CE.way efficacy testing laboratory

Redness in the skin, also known as erythema, is a common skin reaction that occurs due to the dilatation of blood vessels near skin's surface. There are various factors, including environmental factors, allergic reactions, skin conditions (rosacea, eczema, psoriasis), skin sensitivity, irritants (harsh chemicals, abrasive skincare products), infections, inflammation disorders (lupus), sunburn.

The process of redness in the skin involves blood vessel dilatation, inflammation, vasodilation, and nerve activation. The duration and intensity of redness can vary, it can be mild and temporary (exercise, temperature) or prolonged and severe (rosacea, sunburn).

Tailored to your product

A protocol built for your claims.

Efficacy testing protocol is prepared for each product individually with close cooperation with the sponsor. Based on the claims, usage regime and efficacy expectations, we prepare a protocol that is suitable for the type of product and can confirm product efficacy. The studies can be performed over a different time period (from a few days to several weeks or months) depending on the claim and type of measurement.

Get started

Ready to substantiate your redness reduction claims?

Speak with our experts about an efficacy testing protocol tailored to your cosmetic product.

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