Efficacy testing

Efficacy testing: skin moisturizing and hydration

Study design

General skin testing protocol

Number of subjects

20 (determined by client)

Place of application

Face / Arm / Thigh (determined by client)

Testing time

4 weeks (determined by client)

Sample requirement

Equal to the number of subjects

Measurement points

  • T0 – before application (cleaned skin surface, adaptation time 20 min)
  • Tx – after x weeks (determined by client)

Procedure

  • Washout phase at least 2 h before the measurement
  • 3–5 measurements on the testing site (“BEFORE testing”)
  • Product used by participants at home during the testing period
  • 3–5 measurements on the testing site (“AFTER testing”)

Equipment

  • Demaflex / Dermalab (Cortex Technologies)
  • Soft FX (Callegari, 1930)
  • EVE M Panoramic AI skin analyzer
What to look for

Signs of skin dehydration.

Cosmetic serum sample in the testing laboratory

Skin dehydration occurs when the skin lacks adequate moisture and water. Skin can appear dull, dry and less supple.

Common signs are rough texture, tightness and discomfort, flakiness and peeling, increased sensitivity, redness, decreased elasticity and also fine lines and wrinkles.

Claims related to hydration

  • Moisturizing
  • Hydrating
How we measure

Measurement principles and instruments.

Skin hydration measurement with Dermalab

To prove moisturizing and hydrating claims we measure the following parameters using the following instruments:

Evaluation of skin hydration

  • Dermalab (Cortex Technologies)
  • Soft FX (Callegari, 1930)
Proven efficacy

See our results.

Graph visualisation

Graph visualisation

Graph visualisation

Graph visualisation

The science

Skin hydration.

Evaluating efficacy test results

Skin hydration is important for normal functioning of the skin and is primarily linked to the ability of the stratum corneum to retain water. While the amount of water in the inner layers of the skin is relatively constant. Adequate hydration is essential for maintaining healthy, plump, and radiant skin.

The process of hydration involves mechanisms like natural moisturizing factors, stratum corneum which prevents excessive water loss, sebum which maintains hydration by preventing excessive evaporation of water, water intake, hydrating skincare products.

Tailored to your product

A protocol built for your claims.

Efficacy testing protocol is prepared for each product individually with close cooperation with the sponsor. Based on the claims, usage regime and efficacy expectations, we prepare a protocol that is suitable for the type of product and can confirm product efficacy. The studies can be performed over a different time period (from a few days to several weeks or months) depending on the claim and type of measurement.

Get started

Ready to substantiate your hydration claims?

Speak with our testing experts about an efficacy study tailored to your product's claims, usage regime and timeline.

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