Efficacy testing: sebum regulating, mattifying effect
General skin testing protocol
Number of subjects
20 (determined by client)
Place of application
Face / Arm / Thigh (determined by client)
Testing time
4 weeks (determined by client)
Sample requirement
Equal to the number of subjects
Measurement points
- T0 – before application (cleaned skin surface, adaptation time 20 min)
- Tx – after x weeks (determined by client)
Procedure
- Washout phase at least 2 h before the measurement
- 3–5 measurements on the testing site (“BEFORE testing”)
- Product used by participants at home during the testing period
- 3–5 measurements on the testing site (“AFTER testing”)
Equipment
- Demaflex / Dermalab (Cortex Technologies)
- Soft FX (Callegari, 1930)
- EVE M Panoramic AI skin analyzer
Signs of increased sebum production
Signs of increased sebum production
Increased sebum production can lead to oily skin and may be associated with certain signs and symptoms.
Most common are oily skin (T-zone), enlarged pores, acne breakouts, thicker and rougher skin texture, shiny skin, and red, inflamed skin due to acne breakouts.
Claims related to sebum production
- Sebum regulating
- Mattifying effect
Measurement principles and instruments
Measurement principles and instruments
To prove sebum production related claims we measure the following parameters using the following instruments:
Evaluation of sebum
- Dermalab (Cortex Technologies)
- Soft FX (Callegari, 1930)
See our results
Sebum production
Sebum production
Sebum is produced by sebaceous glands, which are distributed all over the skin except on the palms and soles of the feet. Sebum is secreted onto the skin and hair surface, where it plays a crucial role as a protectant by creating a thin film on the surface of stratum corneum and maintaining overall moisture balance. Sebum is a complex mix of lipids and consists of triglycerides, wax esters, cholesterol esters, squalene as well as free cholesterol and fatty acids.
Regulating sebum production is essential for maintaining balanced and healthy skin. Both excessive sebum production (seborrhea) and insufficient sebum production can lead to skin issues.
Seborrhea is usually associated with oily skin type and linked to genetic factors but may also happen in subjects with non-greasy skin in specific stages of life such as adolescents, post-menopausal (due to hormonal changes), or it can also be triggered by stress or medication.
A protocol built for your claims.
Efficacy testing protocol is prepared for each product individually with close cooperation with the sponsor. Based on the claims, usage regime and efficacy expectations, we prepare a protocol that is suitable for the type of product and can confirm product efficacy. The studies can be performed over a different time period (from a few days to several weeks or months) depending on the claim and type of measurement.
Ready to substantiate your sebum regulating claims?
Speak with our testing experts about an efficacy study tailored to your product's claims, usage regime and timeline.
