Efficacy testing: anti-wrinkle
General skin testing protocol
Number of subjects
20 (determined by client)
Place of application
Face / Arm / Thigh (determined by client)
Testing time
4 weeks (determined by client)
Sample requirement
Equal to the number of subjects
Measurement points
- T0 – before application (cleaned skin surface, adaptation time 20 min)
- Tx – after x weeks (determined by client)
Procedure
- Washout phase at least 2 h before the measurement
- 3–5 measurements on the testing site (“BEFORE testing”)
- Product used by participants at home during the testing period
- 3–5 measurements on the testing site (“AFTER testing”)
Equipment
- Demaflex / Dermalab (Cortex Technologies)
- Soft FX (Callegari, 1930)
- EVE M Panoramic AI skin analyzer
Signs of wrinkles
Signs of wrinkles
The signs of wrinkles can vary in severity and location, the most common are fine lines, deep furrows, marionette lines, nasolabial folds, lip lines, neck wrinkles, crow's feet, forehead lines.
They commonly develop in areas of the skin that are exposed to the sun and are subject of repeated movements due to facial expressions such as smiling, squinting, raising eyebrows.
Claims related to skin ageing
- Anti-wrinkle
Measurement principles and instruments.
Measurement principles and instruments.
To prove anti-aging claims, we measure the following parameters using the following instruments:
- EVE M Panoramic AI skin analyzer
See our results.
Skin wrinkles.
Wrinkles are common sign of ageing and occur because of various biological processes that affect the skin's structure and function. They are visible lines, creases, or folds that appear on the skin's surface.
Elastin and collagen
Crucial proteins that provide support and elasticity of the skin. As we age, the production of these proteins decreases, leading to a loss of skin firmness and development of wrinkles.
Dehydration and loss of moisture
Also a result of ageing. As we age, the skin's ability to retain moisture diminishes, leading to dryness and appearance of wrinkles.
Free radical damage
Occurs because of exposure to environmental factors such as UV radiation or pollution. These unstable molecules can damage skin cells, leading to premature aging and formation of wrinkles.
Muscle contraction
Due to facial expressions causes dynamic wrinkles, also known as expression lines. Over time, these repetitive movements lead to formation of lines, such as crow's feet and forehead wrinkles.
A protocol built for your claims.
Efficacy testing protocol is prepared for each product individually with close cooperation with the sponsor. Based on the claims, usage regime and efficacy expectations, we prepare a protocol that is suitable for the type of product and can confirm product efficacy. The studies can be performed over a different time period (from a few days to several weeks or months) depending on the claim and type of measurement.
Ready to substantiate your anti-wrinkle claims?
Speak with our experts about an efficacy testing protocol tailored to your cosmetic product.
