Efficacy testing: anti-ageing

To prove anti-aging claims, we measure the following parameters using the following instruments:

Skin ageing is a natural process caused by a combination of external(extrinsic) and internal (intrinsic) factors. Both types of factors can lead to a loss of structural integrity and reduced skin function. Understanding the mechanisms of cellular ageing and the effects of different factors on the skin can help identify ways to influence premature skin ageing and reduce visible signs of ageing.

Extrinsic skin ageing results from environmental and lifestyle factors, such as exposure to sunlight, pollution, smoking, diet, and skincare habits. The strong effects of ultraviolet (UV) radiation on the skin are commonly referred to as photoageing. Unlike intrinsic ageing, extrinsic skin ageing can be prevented, alleviated, or reduced to a certain degree.

Intrinsic, or chronological, skin ageing is a biologically determined process influenced by genetics, time, and internal physiological changes. It is an inevitable process that affects every individual, although the rate and visible effects vary from person to person. Hormonal changes, such as reduced estrogen levels, are another important internal factor that can significantly affect skin ageing.

A major mechanism involved in extrinsic skin ageing is oxidative stress. The skin's antioxidant defence capacity may decrease with age, making it more vulnerable to damage. Oxidative stress is strongly associated with exposure to UV radiation, which generates reactive oxygen species (ROS), including free radicals. These reactive molecules contribute to premature ageing by damaging DNA and promoting the breakdown of extracellular matrix components, such as collagen, elastin, and hyaluronic acid. Prolonged UV exposure can also promote inflammatory processes and contribute to local immunosuppression in the skin.