Efficacy testing

Efficacy testing: skin sensitivity evaluation, anti-irritating

Study design

General skin testing protocol

Number of subjects

20 (determined by client)

Place of application

Face / Arm / Thigh (determined by client)

Testing time

4 weeks (determined by client)

Sample requirement

Equal to the number of subjects

Measurement points

  • T0 – before application (cleaned skin surface, adaptation time 20 min)
  • Tx – after x weeks (determined by client)

Procedure

  • Washout phase at least 2 h before the measurement
  • 3–5 measurements on the testing site (“BEFORE testing”)
  • Product used by participants at home during the testing period
  • 3–5 measurements on the testing site (“AFTER testing”)

Equipment

  • Demaflex / Dermalab (Cortex Technologies)
  • Soft FX (Callegari, 1930)
  • EVE M Panoramic AI skin analyzer
What to look for

Signs of sensitive skin

Skin analysis results on the EVE M skin analyzer screen

Skin sensitivity is characterized by heightened sensitivity and reactivity, often leading to discomfort, irritation, redness, itching, stinging, burning, which may be accompanied by erythema. Sensitive skin may be prone to dryness, rashes, and breakouts.

Claims related to skin sensitivity

  • Anti-irritating
  • For sensitive skin
How we measure

Measurement principles and instruments

Reviewing before and after EVE M facial images

To prove skin sensitivity claims we measure the following parameters using the following instruments:

  • Skin sensitivity evaluation with before / after face imaging
    • EVE M Panoramic AI skin analyzer
  • Patch test
Proven efficacy

See our results

EVE M Panoramic AI skin analyzer

Before/after results of skin sensitivity

Before/after results of skin sensitivity

The science

Skin sensitivity

Participant during EVE M skin analysis

Sensitive skin is a condition of hyperreactivity to environmental factors or topically applied products. Skin sensitivity is associated with disrupted skin barrier function, which causes increased transepidermal water loss (TEWL). It also allows penetration of irritants, environmental pollutants, or cosmetic products.

Sensitive skin can be characterized by a spectrum of symptoms and can be divided into 4 subtypes: acne type (prone to acne, blackheads, whiteheads), rosacea type (prone to redness, flushing and hot sensations), stinging type (tendency to burning or stinging sensations) and allergic type (prone to skin flaking, itching and erythema). But they all share one common factor, that is inflammation.

Tailored to your product

A protocol built for your claims.

Efficacy testing protocol is prepared for each product individually with close cooperation with the sponsor. Based on the claims, usage regime and efficacy expectations, we prepare a protocol that is suitable for the type of product and can confirm product efficacy. The studies can be performed over a different time period (from a few days to several weeks or months) depending on the claim and type of measurement.

Get started

Ready to substantiate your sensitive-skin claims?

Speak with our testing experts about an efficacy study tailored to your product's claims, usage regime and timeline.

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